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ORIGINAL ARTICLE
Year : 2018  |  Volume : 6  |  Issue : 1  |  Page : 33-37

Calculation of the reference bone mineral density values in North Indian population using phantomless quantitative computed tomography


1 Department of Radiodiagnosis, Dr. RPGMC, Kangra, Himachal Pradesh, India
2 Department of Radiodiagnosis, Sterling Hospitals, Ahmedabad, Gujarat, India

Correspondence Address:
Dr. Rohit Bhoil
Department of Radiodiagnosis, Dr. RPGMC, Kangra, Himachal Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/joas.joas_12_18

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OBJECTIVE: The objective of the study is to generate reference values of bone mineral density(BMD) in north Indian population using phantomless quantitative computed tomography(QCT). MATERIALS AND METHODS: Bone mineral densities were generated from the computed tomography(CT) scans of 691patients(390males and 301females, ages 11–85years) who underwent CT of the abdomen or thorax for indications unrelated to bone diseases. The individuals were divided according to age groups from 11–15 to 80–85years. BMD was calculated by phantomless QCT software by assessing L1 and L2 vertebrae. RESULTS: For females, the maximum BMD was observed for the age group of 21–25years (144.67mg/cc). The overall bone loss per year from 26 to 85years was 1.62mg/cc. Greater bone loss was seen from ages of 36–55years which was 2.18mg/cc. With bone loss per year being 0.99mg/cc in ages from 26 to 35years and 1.41mg/cc from 56 to 85years. Regression analysis gave a better fit using third order polynomial of age than did a linear regression line. For males, the maximum BMD was observed for the age group of 21–25years(147.67mg/cc). The overall bone loss per year from 26 to 85years was 1.2mg/cc. Regression analysis gave the best fit using linear regression. CONCLUSION: In the study population, the males show a linear relationship between age and BMD with continuous bone loss after the age of 25years while females demonstrate a more complex relationship between age and BMD with accelerated bone loss in perimenopausal age group.


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